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Research shows that various cannabinoids such as THC and CBD can help people to better cope with pain, particularly chronic pain. This is one of the reasons that medicinal cannabis is becoming more and more accepted as a way of relieving pain in patients with cancer. For the treatment of MS there is even a registered drug that contains a combination of THC and CBD (called Savitex). However, scientific research provides growing evidence that extracts of whole plants (from the cannabis family) have a better therapeutic effect than a few isolated cannabinoids [1]. Whole plant extracts consist of a complex mix of cannabinoids and non-cannabinoid components. It seems that these components create a synergistic effect that is superior to that of single, pure components [2]. Multiple studies on the extent to which animals are sensitive to pain stimuli seem to point this out exactly. For example, studies have been performed in which whole plant extracts were compared to extracts containing only CBD and THC. These studies show that whole plant extracts succeed better in promoting pain tolerance in test animals and making them less sensitive to pain as well [3]. Other studies have shown that cannabinoids such as THCV, CBG and CBC can also help combat pain. Future research must learn us what the characteristics of these cannabinoids are exactly and how they work synergistically against pain.


Advice for use of cannabinoids in pain

Use a so-called Full Spectrum oil, which is an oil that contains a whole spectrum of cannabinoids. Based on scientific research, there is evidence that these cannabinoids are effective against pain: THC, CBD, THCV, CBG and CBC. Click here to read more about safe use of cannabinoids.




  1. Sofia, R.D., Vassar, H.B., and Knobloch, L.C. (1975). Comparative analgesic activity of various naturally occurring cannabinoids in mice and rats. Psychopharmacologia, 40(4): 285-295.
  1. Russo, E.B. and Mcpartland, J.M. (2003). Cannabis is more than simply delta(9)-tetrahydrocannabinol. Psychopharmacology (Berlin), 165(4): 431-432.
  1. Comelli, F., Giagnoni, G., Bettoni, I., Colleoni, M., and Costa, B. (2008). Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved. Phytotherapy Research, 22(8): 1017-1024.





1 Comment

  1. Ik maak THC en CBD olie zelf, volgens de Simpson methode. Dat doe ik, sinds de kanker van mijn oma. Het bleek toen erg lastig, aan THC olie te komen of tegen absurde prijzen. De overheid zou het daarom meer toegankelijk moeten maken…
    Zelf gebruik ik het voor mijn slaapproblemen en mijn vrouw voor haar spierziekte. Het is overal goed voor!

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